First Paper from the APEX Project Published

Our first paper from the APEX (Aphasia Physical EXercise) project has been published in Aphasiology!
In this pilot study, we explored the feasibility of a high-intensity exercise program specifically designed for stroke survivors with aphasia, as well as its potential to support language, cognitive, and physical outcomes.
This was a small first study, but an important step toward a larger goal: understanding how physical exercise can serve as an adjuvant intervention for aphasia recovery—helping people not only improve their physical fitness but potentially support cognitive and language recovery as well.
The findings from this work helped pave the way for our ongoing larger clinical trial, where we are continuing to investigate these questions more rigorously.
We are excited to see where this work takes us.

Below you can read the first paper; more to come—stay tuned!

Recruiting for a New Exercise Cohort!

We are excited to announce that recruitment for our study is once again open! We are seeking individuals with post-stroke aphasia who are interested in participating in a regular exercise program.


The goal of this study is to better understand how different types of exercise may improve fitness, mobility, cognition, language, and overall well-being after stroke. The study includes assessments before and after the exercise program, as well as group exercise sessions held three times per week for 12 weeks. Some sessions will take place in person, while others will be conducted via Zoom.

For more information about the study, please visit our Current Study page

The next exercise cohort is scheduled to begin in early September, with pre-intervention assessments taking place in late July and August.

If you are interested in learning what exercise can do for you, please reach out to our team. We would love to hear from you!

APEX TEAM at ACSM!

The APEX research team, including Drs. Maria Ivanova and Christian Thompson, along with student researcher Lauren Cervantes from the University of San Francisco, presented their poster, “Feasibility of a Remotely Delivered High-Intensity Functional Training Program in Individuals with Post-Stroke Aphasia,” at the American College of Sports Medicine (ACSM) Annual Meeting.

The team enjoyed sharing their pilot work on the APEX project with colleagues from around the
world and learning about the latest developments in exercise science and rehabilitation research.

The conference provided an exciting opportunity to exchange ideas and highlight the potential of exercise interventions to improve the lives of individuals across the lifespan.

The First Cohort of Participants Has Completed the Study!

We are excited to celebrate an important milestone for the APEX project: our first cohort of participants has completed both the exercise intervention and the post-intervention assessments.

It has been a privilege to work with this amazing group of individuals throughout their exercise journey. Participants enjoyed their time in the study and are looking forward to continuing to stay active and participate in exercise programs within their communities. We are grateful for their dedication and enthusiasm and look forward to welcoming future cohorts to the APEX study!

Our Exercise Intervention Has Officially Begun!

We’re excited to share that the exercise intervention for our first cohort of stroke survivors is now underway as part of our NIH-funded clinical trial. Our participants are enthusiastic and ready to commit to regular exercise as they work toward becoming stronger and fitter over the next 12 weeks.

We’re thrilled to begin this journey together and look forward to sharing updates along the way, so stay tuned!

Enrolling for our new exercise study!

New physical exercise study!

We are currently recruiting cohorts for a new Exercise Based Aphasia study! If you or a loved one is diagnosed with Aphasia after a stroke and wants to be a part of a new study that attempts to understand how different exercises can improve fitness, motor, cognitive, and language abilities. This novel research opens the door to new treatments for stroke recovery!

Who can join


You can take part if you:
– had a stroke and now have aphasia (language problems)
– can walk on your own (using a single-point cane is OK)
– can safely do regular exercise

Interested?

Want to be active and contribute to science? Check out our current study page to learn more!

New NIH Funding to Advance our Aphasia Recovery Research


We are thrilled to announce that our team just received a new R01 grant from the National Institute on Deafness and Other Communication Disorders (NIDCD)R01DC022663; PI: Dr. Maria Ivanova. This exciting new project titled “Exercising language: Behavioral and neurophysiological changes after high-intensity exercise training in post-stroke aphasia” is a direct continuation of our prior work on exercise and aphasia. In this project we will explore how high-intensity physical exercise, a promising yet underutilized adjuvant intervention, can enhance language, cognition, brain health, and emotional well-being in stroke survivors with aphasia.

Building on the encouraging findings from our pilot work, the new grant will enable us to launch a large-scale clinical trial to:

Evaluate how high-intensity exercise influences language, cognitive, motor, and psychosocial outcomes

Examine how improvements in physical fitness relate to gains in communication and cognitive skills

Investigate the neurovascular mechanisms that link exercise to recovery in the brain

This award marks an exciting next step in the APEX Team’s mission to uncover innovative, evidence-based ways to support holistic recovery after stroke.

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Participation in the Stroke Onward Panel


Dr. Maria Ivanova took part in a panel discussion hosted by Stroke Onward, titled “Stronger Together: Community Programs Supporting the Emotional Journey in Recovery for People with Aphasia.” Panelists and audience members explored ways to engage people with aphasia in program designexpand facilitation models and peer-led groups, and build stronger partnerships across clinical, educational, research, and community settings. Through these collaborative discussions—and the actions that follow—the APEX Team aims to enhance quality of life and promote sustainable, inclusive support for stroke survivors with aphasia and their families throughout every stage of recovery.

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APEX Team Presents Innovative Research on Remote Stroke Recovery Intervention

 University of San Francisco undergraduate Lauren Cervantes and co-investigator Dr. Christian Thompson represented the study team at the Southwest Chapter of the American College of Sports Medicine (ACSM) Annual Meeting in Burbank, California.

Their poster presentation shared exciting findings from the Spring 2025 pilot project, which demonstrated that stroke survivors with aphasia can successfully participate in a remotely delivered high-intensity functional training program. This work highlights a promising new avenue for making exercise-based recovery more accessible to individuals living with aphasia.

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